Blood is irradiated in order to prevent a potentially fatal complication of blood transfusion called Transfusion Associated Graft versus Host Disease (TA-GVHD). Irradiated blood is typically used for immunocompromised patients including:
However, TA-GVHD can also occur in other patients when receiving blood from a close relative.
The FDA recommends that blood be irradiated to a minimum dose of 15 Gy (1500 Rads) and a maximum dose of 50 Gy (5000 Rads). Typically 25Gy (2500 Rads) is set to achieve this goal.
RadTag® was developed to meet the FDA requirement and indicate whether the delivered dose of radiation is within the specified range.
RadTag® is the only indicator on the market which can verify compliance with the minimum and maximum dose levels.
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